Antonio, M., Muñoz de la Peña, A., Goicoechea, H. C., & Alcaraz, M. R. (2025). How excitation-emission matrices have revolutionised multi-way data analyses – A tutorial for multi-way EEM-based calibration method developments. Analytica Chimica Acta, 1360, 344089.  https://doi.org/10.1016/j.aca.2025.344089 

Alcaraz, M. R., Montemurro, M., Pisano, P. L., Lombardi, J. M., & Bortolato, S. A. (2025). Functional data analysis, a comprehensive framework for processing non-quadrilinear and low-selective data provided by four-way liquid chromatography analysis. Analytica Chimica Acta, 1356, 344044. https://doi.org/10.1016/j.aca.2025.344044 

Chiappini, F. A., Alcaraz, M. R., & Forzani, L. (2025). A bootstrap-assisted methodology for the estimation of prediction uncertainty in multilayer perceptron-based calibration. Analytica Chimica Acta, 1353, 343954.   https://doi.org/10.1016/j.aca.2025.343954 

Morales, J. M. N., Alcaraz, M. R.*, Loto, A., Parellada, E. A., Tulli, F., Morán Vieyra, F. E., & Borsarelli, C. D. (2024). Chemometric modeling of spectroscopic data for characterizing the visible-light-driven photocatalytic N-dealkylation of rhodamine B on a TiO₂ film. Photochemistry and Photobiology, 100(1), 1–13. https://doi.org/10.1111/php.14043  

Maccio, S. A., Alaniz, R. D., Pierini, G. D., Zon, M. A., Arébalo, F., Fernandez, H., Goicoechea, H., Robledo, S. N., & Alcaraz, M. R.* (2024). A straightforward electrochemical approach for the simultaneous determination of thymol and carvacrol in essential oils. Chemosensors, 12(9), 197. https://doi.org/10.3390/chemosensors12090197

Chiappini, F. A., Pinto, L., Alcaraz, M. R., Omidikia, N., Goicoechea, H. C., & Olivieri, A. C. (2024). Multivariate curve resolution-alternating least-squares and second-order advantage in first-order calibration: A systematic characterisation for three-component analytical systems. Analytica Chimica Acta, 1328, 343159. https://doi.org/10.1016/j.aca.2024.343159

Antonio, M., Alcaraz, M. R., & Culzoni, M. J. (2024). Advances on multiclass pesticide residue determination in citrus fruits and citrus-derived products – A critical review. Environmental Science and Pollution Research, 31, 50012–50035. https://doi.org/10.1007/s11356-024-32288-6

Antonio, M., Chiappini, F. A., Goicoechea, H. C., Culzoni, M. J., & Alcaraz, M. R.* (2024). The advantages behind the efforts of performing higher-order calibration methods – A case study. Analytica Chimica Acta, 1319, 342970. https://doi.org/10.1016/j.aca.2024.342970

Romero, S., Alcaraz, M. R., Forzani, L., Minari, R., & Collins, S. E. (2024). Engineering the performance of bioparaffins from soybean oil to mimic mineral waxes: A non-linear chemometric modeling. Journal of the American Oil Chemists’ Society. https://doi.org/10.1002/aocs.12706

Martín-Tornero, E., Durán-Merás, I., Alcaraz, M. R.*, Muñoz de la Peña, A., Galeano-Díaz, T., & Goicoechea, H. C. (2024). Applying multivariate curve resolution modelling combined with discriminant tools on near-infrared spectra for distinguishing between cheese varieties and stages of ripening. Microchemical Journal, 204, 111039. https://doi.org/10.1016/j.microc.2024.111039

Much, D. G., Alcaraz, M. R.*, Camiña, J. M., Goicoechea, H. C., & Azcarate, S. M. (2024). Leveraging the performance of conventional spectroscopic techniques through data fusion approaches in high-quality edible oil adulteration analyses. Talanta Open, 9, 100313. https://doi.org/10.1016/j.talo.2024.100313

Bracho, G. S., Acosta, M. V., Altamirano, G. A., Alcaraz, M. R., Montemurro, M., Culzoni, M. J., Rossetti, M. F., Kass, L., Luque, E. H., & Bosquiazzo, V. L. (2024). Uterine histopathology and steroid metabolism in a polycystic ovary syndrome rat model. Molecular and Cellular Endocrinology, 585, 112198. https://doi.org/10.1016/j.mce.2024.112198

Alcaraz, M. R.*, Espinosa-Mansilla, A., Durán-Merás, I., & Muñoz de la Peña, A. (2024). An optimized methodology for the determination of multiclass organic ultraviolet sunscreens and metabolites in human milk through chromatographic and chemometric resolution. Talanta, 270, 125560. https://doi.org/10.1016/j.talanta.2024.125560

Alcaraz, M. R.*, Sorbello, C., Florez, L. P., & Etchenique, R. (2023). Fast and inexpensive emission-time in-situ setup for upconversion nanoparticle characterization. Microchemical Journal, 194, 109350. https://doi.org/10.1016/j.microc.2023.109350

Antonio, M., Alcaraz, M. R.*, Falcone, R. D., & Culzoni, M. J. (2023). A micellar-enhanced fluorescence photoinduced four-way calibration method for the determination of multiclass pesticides in lemon juice. Analytica Chimica Acta, 1279, 341778. https://doi.org/10.1016/j.aca.2023.341778

Gomez, A. L., Altamirano, G. A., Alcaraz, M. R., Montemurro, M., Schierano-Marotti, G., Oddi, S. L., Culzoni, M. J., Muñoz-de-Toro, M., Bosquiazzo, V. L., & Kass, L. (2023). Mammary gland development in male rats perinatally exposed to propiconazole, glyphosate, or their mixture. Environmental Toxicology and Pharmacology, 101, 104184. https://doi.org/10.1016/j.etap.2023.104184

Gregoret, S. A., Junges, C. M., Culzoni, M. J., Goicoechea, H. C., Teglia C. M., & Gutierrez F. A. (2025). Sustainable and efficient electrochemical determination of octopamine in Apis mellifera for stress monitoring. Talanta, 291, 127801. https://doi.org/10.1016/j.talanta.2025.127801

Montemurro, M., Uriarte, D.A., Goicoechea, H.C., Collins, S.E.., Culzoni M.J. (2023) High-throughput methotrexate sensing strategy based on a chemometrically assisted pH-switchable optical nanosensor. Sensors & Actuators: B. Chemical, 378,133217.

Montemurro, M., Enderle, A.G., Gutierrez, F., Lizarraga, L., Alvarez, I., Goicoechea, H.C., Collins, S.E., Bollini, M., Culzoni, M.J. (2023) A novel optimized polyoxometalate-modified silver nanocomposite. Application to the development of antibacterial textiles.  Materials Today Communications, 35, 106284. 

Montemurro, M., Uriarte, D.A., Collins, S.E., Goicoechea, H.C., Culzoni M.J. (2025) Chemometrically assisted nanosensor for methotrexate determination in the presence of its molecular analog folic acid.  Analytica Chimica Acta 1366 (2025) 344259.

C.M. Teglia, M. Guiñez, S. Cerutti, F.A. Gutierrez, H.C. Goicoechea. (2023) A novel and sustainable pipette-tip solid-phase microextraction testing of six carbon-based nanomaterials as proof of concept for the determination of sixteen emerging pollutants from active veterinary principles. Green Anal. Chem. 5, 100060. https://doi.org/10.1016/j.greeac.2023.100060

Carla M. Teglia, Sofía A. Gegenschatz, Celina M. Monzón, Héctor C. Goicoechea, Arsenio Muñoz de la Peña, Fabiana A. Gutierrez. (2024) Quantitation of three benzimidazole compounds in milk combining effervescence-assisted dispersive liquid–liquid microextraction with electrochemical detection using carbon nanotube-electropolymerized L-DOPA modified sensor. Microchem. J. 201, 110608. https://doi.org/10.1016/j.microc.2024.110608

Carla M. Teglia, Hernán R. Hadad, Nora Uberti‑Manassero, Álvaro S. Siano, María R. Repetti, Héctor C. Goicoechea, María J. Culzoni, María A. Maine. (2024) Removal of enrofloxacin using Eichhornia crassipes in microcosm wetlands. Environ. Sci. Pollut. Res. 31, 14845-14857. https://doi.org/10.1007/s11356-024-32146-y

Nicolás A. Aschemacher, Álvaro S. Siano, Carla M. Teglia, Héctor C. Goicoechea. (2025) Development, optimization and comparison of solid–liquid and liquid–liquid microextraction for the determination of four flavonols in Schinus molle L. using high‑performance liquid chromatography coupled with second‑order data modeling. Anal Bioanal Chem. 417, 1381-1392. https://doi.org/10.1007/s00216-024-05700-3 417

Carla Mariela Teglia, Fabiana Andrea Gutierrez, Selva Machado, Hernán Ricardo Hadad, María Alejandra Maine, and Héctor Casimiro Goicoechea. (2025) Spatial occurrence of emerging contaminants in rivers and wastewater. Analysis of environmental and human risks. Environ. Toxicol. Chem, 44, 397-409. https://doi.org/10.1093/etojnl/vgae075

Nicolás A. Aschemacher, Sofía A. Gegenschatz, Carla M. Teglia, Álvaro S. Siano, Fabiana A. Gutierrez, Héctor C. Goicoechea. (2024) Highly sensitive and selective electrochemical sensor for simultaneous determination of gallic acid, theophylline and caffeine using poly(L-proline) decorated carbon nanotubes in biological and food samples. Talanta 267, 125246. https://doi.org/10.1016/j.talanta.2023.125246

Nicolás A. Aschemacher, Carla M. Teglia, Álvaro S. Siano, Fabiana A. Gutierrez, Héctor C. Goicoechea. (2024) Development of an electrochemical sensor using carbon nanotubes and hydrophobic natural deep eutectic solvents for the detection of α-glucosidase activity in extracts of autochthonous medicinal plants. Talanta 268, 125313. https://doi.org/10.1016/j.talanta.2023.125313

Sofía A. Gegenschatz, Carla M. Teglia, Celina M. Monzón, Héctor C. Goicoechea, Fabiana A. Gutierrez. (2025) A novel strategy for the quantify of emerging isomeric pollutants belonging to the dihydroxybenzene family for environmental sample monitoring by amperometric detection. Talanta 281, 126818. https://doi.org/10.1016/j.talanta.2024.126818

Julián Elías Abud, Romina Pagotto, Valentina Galliani, Carla Teglia, Julia Culzoni, Mariela Bollati-Fogolín, Maria Laura Zenclussen, Horacio Adolfo Rodríguez. (2024) In vitro blastocyst implantation and trophoblast migration are disrupted by the UV filter benzophenone-3 (BP3). Environ. Pollut. 349, 123840. https://doi.org/10.1016/j.envpol.2024.123840

Constanza J. Venegas, Fabiana A. Gutierrez, Nik Reeves-McLaren, Gustavo A. Rivas, Domingo Ruiz-León and Soledad Bollo (2023) In situ or Ex situ Synthesis for Electrochemical Detection of Hydrogen Peroxide—An Evaluation of Co2SnO4/RGO Nanohybrid Micromachines,14, 1059.

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Alcaraz, M. R., & Etchenique, R. (2024). Chapter 2: Custom-made optical platforms for high-throughput acquisition of multilinear high-order data in dynamic systems. En A. Escandar, G. Goicoechea, & A. Muñoz de la Peña (Eds.), Fundamentals and Applications of Multiway Data Analysis (Vol. 33, pp. 25–39). Elsevier. https://doi.org/10.1016/B978-0-443-13261-2.00021-7

Schwaighofer, A., Alcaraz, M. R., & Lendl, B. (2024). Chapter 12: Recent applications of multiway data modeling for protein analysis by IR spectroscopy. En A. Escandar, G. Goicoechea, & A. Muñoz de la Peña (Eds.), Fundamentals and Applications of Multiway Data Analysis (Vol. 33, pp. 279–299). Elsevier. https://doi.org/10.1016/B978-0-443-13261-2.00010-2

Alcaraz, M. R., Monago-Maraña, O., Goicoechea, H. C., & Muñoz de la Peña, A. (2024). Chapter 15: Recent applications of third-order/four-way and fourth-order/five-way data analysis. En A. Escandar, G. Goicoechea, & A. Muñoz de la Peña (Eds.), Fundamentals and Applications of Multiway Data Analysis (Vol. 33, pp. 337–362). Elsevier. https://doi.org/10.1016/B978-0-443-13261-2.00023-0

Fabricio A. Chiappini, Carla M. Teglia, Silvana M. Azcarate, and Hector C. Goicoechea (2023). Chapter 2: Fundamentals of Design of Experiments and Optimization: Designs for Factor Screening and Data Analysis in Pre-Response Surface Methodology. In: Introduction to Quality by Design in Pharmaceutical Manufacturing and Analytical Development. Ed. Springer Nature. ISBN: 978-3-031-31504-6 Páginas: 29-45

Silvana M. Azcarate, Carla M. Teglia, Fabricio A. Chiappini and Hector C. Goicoechea (2023) Chapter 3: Fundamentals of Design of Experiments and Optimization: Experimental Designs in Response Surface Methodology. In: Introduction to Quality by Design in Pharmaceutical Manufacturing and Analytical Development.  Ed. Springer Nature. ISBN: 978-3-031-31504-6 Páginas: 47-66

Fabricio A. Chiappini, Silvana M. Azcarate, Carla M. Teglia, and Hector C. Goicoechea. (2023) Chapter 4: Fundamentals of Design of Experiments and Optimization: Data Modeling in Response Surface Methodology. In: Introduction to Quality by Design in Pharmaceutical Manufacturing and Analytical Development. Ed. Springer Nature. ISBN: 978-3-031-31504-6 Páginas: 67-89

P.M. Peltzer, A.P. Cuzziol Boccioni, C. Martinuzzi, A. Bassó, A.M. Attademo, M.J. Culzoni, L. Paradina-Fernandez, R.C. Lajmanovich. (2023) Chapter 5: Ecotoxicity and Risk Assessment Characterization of Veterinary Pharmaceuticals on Anuran Amphibian Larvae. In: Amphibian Species in Environmental Risk Assessment Strategies. Royal Society of Chemistry. PDF ISBN: 978-1-83767-200-4.

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• V Jornadas de Jovenes Bionanocientíficos (Ciudad Autónoma de Buenos Aires, Argentina, 2023). Nueva plataforma nanosensora asistida por quimiometría para la determinación de análogos moleculares. D.A. Uriarte, M. Montemurro, S.A. Gregoret, M. Garrido, H.C. Goicoechea, S.E. Collins, M.J. Culzoni. 
• Conferentia Chemometrica 2023. Sopron, Hungria, 10-13 septiembre de 2023. “Higher-order data analysis to leverage the performance of food quality control procedures”. M.R. Alcaraz, M. Antonio, F. Chiappini, M.J. Culzoni, J. Zaldarriaga Heredia, S.M. Azcarate, J.M. Camiña, H.C. Goicoechea.
• XIX Chemometrics in Analytical Chemistry, Santa Fe, Argentina, 9 al 12 de septiembre de 2024:

Poster: 

“Assessing the analytical improvements of data fusion strategies for the chromatographic determination of multiclass pesticides.” M. Antonio, M.R. Alcaraz, M. Montemurro, M.J. Culzoni

“Methotrexate quantitation in the presence of its molecular analog folic acid using silver nanoclusters and chemometric modeling”. D.A. Uriarte, M. Montemurro, H.C. Goicoechea, M.J. Culzoni. 

• 10th International Symposium on Wetland Pollutant Dynamics and Control. 10–14 September 2023 Bruges, Belgium. Presentación oral: “Removal of enrofloxacin using Eichhornia crassipes in wetlands at microcosm scale”. Carla M. Teglia, Hernán R. Hadad, Nora Uberti-Manassero, Álvaro S. Siano, María R. Repetti, Héctor C. Goicoechea, María J. Culzoni, María A. Maine.
• XII Congreso Argentino de Química Analítica. San Juan, 12 al 15 de septiembre de 2023. 

Presentación oral:

“Estudio de la presencia de BP3, 4MBC y BPA en plasma. Desarrollo y comparación de métodos analíticos”. Carla M. Teglia, Fabiana A. Gutierrez, Ma. Julia Culzoni, M, Laura Zenclussen, Horacio Rodriguez, Héctor C. Goicoechea.

Poster: 

“Desarrollo de un biosensor electroquímico utilizando nanotubos de carbono y NADES hidrofóbico para la detección de la actividad de α glucosidasa en extractos de plantas medicinales autóctonas””. Fabiana A. Gutierrez, Nicolás A. Aschemacher, Carla M. Teglia, Álvaro S. Siano.

“Microextracción dispersiva favorecida por efervescencia para la determinación de benzimidazoles en leche mediante detección electroquímica basada en nanotubos de carbono decorados con L DOPA electropolimerizada”. Carla M. Teglia, Fabiana A. Gutiérrez, Arsenio Muñoz de la Peña, Héctor C. Goicoechea.

“Determinación electroquímica de teofilina, cafeína y ácido gálico mediante nanotubos de carbono decorados con poli(L-prolina) en muestras biológicas y alimentarias”. Fabiana A. Gutierrez, Nicolás A. Aschemacher, Sofía A. Gegenschatz, Álvaro S. Siano, Carla M. Teglia, Héctor C. Goicoechea.

“Construcción de un sensor electroquímico basado en el uso de nanomateriales híbridos para la cuantificación simultánea de vitaminas e isoflavonas”. Sofía A. Gegenschatz, Carla M. Teglia, Fabiana A. Gutierrez, Christian J. Sequin.

“Nueva plataforma basada en nanoclusters metálicos y cationes polivalentes para la determinación espectrofluorimétrica de metotrexato en presencia de un análogo molecular”. D.A. Uriarte, M. Montemurro, S. Gregoret, M. Garrido, M.J. Culzoni. XII Congreso Argentino de Química Analítica (San Juan, Argentina, 2023).

“Desarrollo de un método cromatográfico-quimiométrico para la determinación de agroquímicos en aceites esenciales cítricos”. M. Antonio, M.R. Alcaraz, M. Montemurro, M.J. Culzoni. XII Congreso Argentino de Química Analítica (San Juan, Argentina, 2023).

Conferencia plenaria:

“Avances recientes en el diseño de estrategias para la exaltación de señales espectroscópicas y su aplicación al desarrollo de métodos analíticos asistidos por quimiometría”. Ma. Julia Culzoni

• “Nanopartículas de oro funcionalizadas con avidina como plataforma versátil para la construcción de nanobiosensores”. S.A. Gregoret, M. Montemurro, F. Gutierrez, S. Collins, M. J. Culzoni. XXIII Encuentro de Superficies y Materiales Nanoestructurados (San Miguel de Tucumán, Tucumán, Argentina. 2025). 

SAT de comitentes múltiples. “Asesoría para desarrollo y validación de métodos analíticos asistidos por quimiometría”. FBCB. UNL. 2023-2025. Responsable: M.J. Culzoni.

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• Premio “2024 Chemometrics and Intelligent Laboratory Systems Award – Elsevier” por las contribuciones realizadas en el desarrollo de aplicaciones quimiométricas en los últimos 5 años. 2024
• “Plataforma nanobiosensora para el diagnóstico in vitro del adenocarcinoma pancreático ductal”. Proyecto finalista del premio Merck – MINCyT- CONICET de Innovación en Ciencias de la Salud edición 2023.

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