Bioquímico // BS degree in Biochemistry

Doctor en Ciencias Biológicas // Ph.D. in Biological Sciences

Profesor Titular // Full Professor

Director de Departamento // Head of Department

Investigador Principal de CONICET // Research Fellow of CONICET

Director del Programa de Biofísica y Biofisicoquímica // Director of the Biophysics and Biophysical Chemistry Program

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Carlos D. Brondino obtuvo los títulos de Bioquímico y Doctor en Ciencias Biológicas en la Universidad Nacional del Litoral (Argentina). Fue estudiante de posdoctorado e investigador en el Departamento de Química de la Universidad Nova de Lisboa, Portugal. Actualmente es profesor titular y director de departamento, investigador principal del CONICET y director del programa de biofísica y biofisicoquímica en el Departamento de Física de la Facultad de Bioquímica y Ciencias Biológicas de la Universidad Nacional del Litoral. Sus intereses de investigación incluyen el rol de los iones metálicos de transición en sistemas de interés biológico, el mecanismo de reacción de metaloenzimas involucradas en los ciclos biológicos del nitrógeno y el azufre y el desarrollo de metodologías basadas en EPR para caracterizar las propiedades magnéticas de sistemas de interés biológico y complejos inorgánicos.

Carlos D. Brondino received B.S. and Ph.D. degrees from Universidad Nacional del Litoral (Argentina). He was a postdoctoral and research fellow in the Department of Chemistry at Universidade Nova de Lisboa, Portugal. He is now a full professor, head of department, a research fellow of CONICET and director of the biophysics and biophysical chemistry program in the Department of Physics in the Facultad de Bioquímica y Ciencias Biológicas at Universidad Nacional del Litoral. His principal research interests concern the role of transition metal ions in systems of biological interest, the reaction mechanism of metalloenzymes involved in the biological cycles of nitrogen and sulfur and the development of EPR-based methodologies to characterize the magnetic properties of systems of biological interest and inorganic complexes.

Publicaciones representativas // Some selected publications

"Magnetic Properties of Weakly Exchange-Coupled High Spin Co(II) Ions in Pseudooctahedral Coordination Evaluated by Single Crystal X-band EPR and Magnetic Measurements" N. I. Neuman, E. Winkler, O. Peña, M. C. G. Passeggi, A. C. Rizzi, C. D. Brondino Inorganic Chemistry 2014, 53, 2535–2544.

"Single Crystal EPR of the Mixed-Ligand Complex of Copper(II) with L-Glutamic Acid and 1,10-Phenanthroline: A Study on the Narrowing of the Hyperfine Structure by Exchange" N. I. Neuman, V. G. Franco, F. M. Ferroni, R. Baggio, M. C. G. Passeggi, A. C. Rizzi, and C. D. Brondino Journal of Physical Chemistry A 2012, 116, 12314-12320.

"Overexpression, purification, and biochemical and spectroscopic characterization of copper-containing nitrite reductase from Sinorhizobium meliloti 2011. Study of the interaction of the catalytic copper center with nitrite and NO" F. M. Ferroni, S. A. Guerrero, A. C. Rizzi, C. D. BrondinoJournal of Inorganic Biochemistry2012, 114, 8-14.

"Kinetic, Structural, and EPR Studies Reveal That Aldehyde Oxidoreductase from Desulfovibrio gigas Does Not Need a Sulfido Ligand for Catalysis and Give Evidence for a Direct Mo-C Interaction in a Biological System" T. Santos-Silva, F. Ferroni, A. Thapper, J. Marangon, P. J. González, A. C. Rizzi, I. Moura, J. J. G. Moura, M. J. Romao, C. D. Brondino Journal of the American Chemical Society 2009, 131, 7990-7998.

"Structural and EPR Studies of Mononuclear Molybdenum Enzymes from Sulfate Reducing Bacteria"Carlos D. Brondino, María G. Rivas, Maria J. Romão, José J. G. Moura, Isabel Moura, Accounts of Chemical Research 2006, 39, 788-796.